Carbapenem and penem antibiotics.III.Synthesis and antibacterial activity of 2-functionalized-methyl penems related to asparenomycines.

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Racemic and optically active 2-(heteroaromatic) thiomethyl penems having a 1-(hydroxymethyl) ethylidene or cyclic carbonate side-chain at C-6 (24,51,63,65,37,40,69 and 21b, 61b, 26b, 30b, 64b, 35b, 66b, 39b, 68b) were synthesized, and their antibacterial activities are determined.

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  • Chem.Pharm.Bull.

    Chem.Pharm.Bull. 33 4371-4381, 1985

    公益社団法人日本薬学会

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