The scent gland and ordinary sebaceous gland of Syrian hamsters and Monogolian gerbils were studied using lectin histochemistry. Male scent glands were larger in size than those of female in both species, but in histochemistry there was no distinct difference between both sexes. Histologically, the scent gland of Syrian hamsters had a strong resemblance to ordinary sebaceous glands, compared to that of Mongolian gerbils. Since the duct of Syrian hamsters was very short, it is difficult to distinguish the duct from the infundibulum. The duct and infudibulum of Mongolian gerbils were larger in diameter than those of Syrian hamsters. The duct widely opened to dermis. Seven lectins (ConA, RCA I, PNA, SBA, UEA-I, DBA and WGA) were used in this study. All of them labelled the differentiated cells of acinus in Syrian hamsters, although SBA did not label those cells in Monolian gerbils. The cells of the duct in Syrian hamsters and Mongolian gerbils were not labelled with SBA. Ordinary sebaceous glands in both species were labelled with all seven lectins. Lectin-binding patterns of scent glands and sebaceous glands were similar in Syrian hamsters. While, in Mongolian gerbils, SBA-binding patterns were different between scent and sebaceous glands. Histologically, the scent gland of Syrian hamsters resembles the sebaceous gland. Therefore, there is a possibility that the scent gland of Syrian hamsters still provides some properties similar to sebaceous gland.