METABOLIC STUDIES OF BILE ACIDS XXI. ‘3β-HYDROXYSTEROL DEHYDROGENASE’ IN RAT LIVER

  • YAMASAKI KAZUMI
    Department of Biochemistry, Tottori University School of Medicine
  • NODA FUMIO
    Department of Biochemistry, Tottori University School of Medicine
  • SHIMIZU KYUTARO
    Department of Biochemistry, Tottori University School of Medicine

Description

1. A partial purification of 3β-hydroxysterol dehydrogenase from rat liver has been described.<br> 2. The enzyme preparation catalyzed the reversible oxidation of 3β-hydroxysterols, regardless of the configuration of the A-B ring junction.<br> 3. DPN+ and TPN+ functioned here equally well as a hydrogen acceptor.<br> 4. The enzyme preparation was inhibited by some sulfhydryl reagents.<br> The authors are indebted to Prof. Dr. L. F. Fieser, Harvard University, for generous gifts of pregnenolone and other steroids. Thanks are due to Miss N. Hatano for her expert technical assistance during the course of this work.

Journal

Details 詳細情報について

  • CRID
    1570291228034198656
  • NII Article ID
    130006877850
  • Text Lang
    en
  • Data Source
    • CiNii Articles

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