Organ specificity and sensitivity to alkaline phosphatase of factors stimulating RNA polymerase II.
-
- NATORI Shunji
- Faculty of Pharmaceutical Sciences, University of Tokyo
-
- SEKIMIZU Kazuhisa
- Faculty of Pharmaceutical Sciences, University of Tokyo
-
- MIZUNO Den'ichi
- Faculty of Pharmaceutical Sciences, University of Tokyo
この論文をさがす
説明
Factors stimulating RNA polymerase II [EC 2. 7. 7. 6] of Ehrlich ascites tumor cells were isolated from homogenates of mouse liver, kidney, and brain. The elution profiles of these factors from phosphocellulose were characteristic for each organ. The molecular size of RNA synthesized in the presence of these factors was much larger than that of RNA synthesized by RNA polymerase II alone.<br> These stimulatory factors lost some of their activity when they were preincubated with alkaline phosphatase [EC 3. 1. 3. 1], suggesting that their phosphate residues are responsible for stimulation of RNA synthesis in vitro.
収録刊行物
-
- The Journal of Biochemistry
-
The Journal of Biochemistry 76 (4), 695-702, 1974
The Japanese Biochemical Society
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1570291228196167936
-
- NII論文ID
- 130003539455
-
- ISSN
- 0021924X
-
- 本文言語コード
- en
-
- データソース種別
-
- CiNii Articles