Modifying Effects of Maharishi Amrit Kalash 4 and 5 on Phagocytic and Digestive Functions of Macrophages in Male ICR Mice
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- SUGIURA Haruo
- Department of Health and Physical Education, Gifu Pharmaceutical University
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- INABA Ryoichi
- Department of Hygiene, Gifu University School of Medicine
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- IWATA Hirotoshi
- Department of Hygiene, Gifu University School of Medicine
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- NISHIDA Hiroyuki
- Department of Health and Physical Education, Gifu Pharmaceutical University
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- TANAKA Takuji
- First Department of Pathology, Gifu University School of Medicine
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説明
A study was carried out to examine modifying effects of Maharishi Amrit Kalash 4 (MAK 4) and Maharishi Amrit Kalashi 5 (MAK 5) on phagocytic and digestive functions of macrophages in male ICR mice. Mice at 4 week of age were divided into 3 groups : no treatment group (control), MAK 4 treated group (MAK 4 group) and MAK 5 treated group (MAK 5 group). MAK 4 and MAK 5 were given p.o. at 50 mg/kg per day (5 days/week) for 7 weeks. Phagocytic function of reticuloendothelial system evaluated by the carbon clearance was enhanced by the treatment of MAK 4 and MAK 5. Superoxide anion (O_<2->) production of peritoneal macrophages increased significantly in both MAK 4 and MAK 5 groups. The acid phosphatase activity of peritoneal macrophages increased significantly in MAK 4 group compared to the control group, but not in MAK 5 group. The activities of β-glucuronidase and lactate dehydrogenase in both MAK 4 and MAK 5 groups increased significantly when compared to the control group. These results suggest that MAK 4 and MAK 5 promote the phagocytic and digestive functions of macrophages and have a stimulatory effect on macrophages.
収録刊行物
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- Environmental health and preventive medicine
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Environmental health and preventive medicine 3 (1), 50-54, 1998-04
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詳細情報 詳細情報について
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- CRID
- 1570572702100481408
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- NII論文ID
- 110002694656
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- NII書誌ID
- AA1108348X
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- ISSN
- 1342078X
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles
