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Adsorption of Catecholamines on a Gold Electrode Surface Studied by Specular Reflection Measurement(Physical,Chemical)
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- TAKAMURA KIYOKO
- Tokyo College of Pharmacy
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- ITO KUNIO
- Tokyo College of Pharmacy
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- KUSU FUMIYO
- Tokyo College of Pharmacy
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Description
The adsorption of catecholamines including norepinephrine, epinephrine, isoproterenol, dopamine, dopa and homocatechol on a gold electrode surface was studied in phosphate buffer of pH 6.9 by specular reflection measurement. Norepinephrine is oxidized at potentials more positive than +0.1 V vs. saturated calomel electrode (SCE) and adsorbed at the potential range from -0.7 to -0.05V. Its antagonists, phenoxybenzamine, tolazoline, ergotamine, oxprenolo! and propranolol, are also adsorbed on the electrode, more strongly than norepinephrine. The adsorption behavior of catecholamines on the electrode surface may reflect electrostatic interactions between adrenergic transmitter substances and their receptors.
Journal
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- Chemical & pharmaceutical bulletin
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Chemical & pharmaceutical bulletin 35 (4), 1327-1333, 1987-04-25
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1570572702348544128
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- NII Article ID
- 110006281058
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- NII Book ID
- AA00602100
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- ISSN
- 00092363
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- Text Lang
- en
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- Data Source
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- CiNii Articles