SYNTHESIS OF SAFRAMYCINS. I. TOTAL SYNTHESIS OF (±)-SAFRAMYCIN B AND ITS CONGENERS.(Communication to the Editor)
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説明
We describe the total synthesis of the dimeric isoquinolinequinone antibiotic saframycin B (1) from tricyclic lactam 3. The key step is the stereoselective intramolecular cyclization of the aminoacetal 6. The structure of the pentacyclic intermediate 8 was confirmed by X-ray crystallography.
収録刊行物
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- Chemical & pharmaceutical bulletin
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Chemical & pharmaceutical bulletin 35 (5), 2158-2161, 1987-05-25
公益社団法人日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1570572702349230976
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- NII論文ID
- 110006281182
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- NII書誌ID
- AA00602100
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- ISSN
- 00092363
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles