Structure of (+)-Epigriseofulvin
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- ITAI AKIKO
- Faculty of Pharmaceutical Sciences, University of Tokyo
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- IITAKA YOICHI
- Faculty of Pharmaceutical Sciences, University of Tokyo
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- NAKAMURA SUZUMI
- Kyoritsu College of Pharmacy
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- ODA TAIKO
- Kyoritsu College of Pharmacy
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- SATO YOSHIHIRO
- Kyoritsu College of Pharmacy
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Description
The crystal and molecular structure of (+)-epigriseofulvin were elucidated by X-ray structure analysis. The crystal belongs to a triclinic space group P1,with the unit cell parameters of a=11.718 (4), b=9.870 (3) Å, α=103.49 (3), β=102.38 (3), γ=96.26 (3)°, V=1061 (1) Å^3. The unit cell contains two crystallographically independent (+)-epigriseofulvin molecules and two chloroform molecules. The structure was solved by the direct method and refined to an R-value of 0.093 for 3971 non-zero reflections. No significant conformational differences between the two molecules were observed. The cyclohexenone rings take half-chair conformations with planar conjugated enone systems.
Journal
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- Chemical & pharmaceutical bulletin
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Chemical & pharmaceutical bulletin 33 (1), 158-164, 1985-01-25
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1570572702507619968
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- NII Article ID
- 110003625115
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- NII Book ID
- AA00602100
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- ISSN
- 00092363
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- Text Lang
- en
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- Data Source
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- CiNii Articles