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An amino acid substitution determining G3m(g).
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- ITO Shigenori
- Department of Legal Medicine, Osaka Medical School
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- YAMAZAKI Kotoyo
- Department of Legal Medicine, Osaka Medical School
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- MIYAZAKI Tokiko
- Department of Legal Medicine, Osaka Medical School
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- MATSUMOTO Hideo
- Department of Legal Medicine, Osaka Medical School
Description
An allotypic G3m(g) marker-specific substitution was studied by sequence analysis of glycopeptides derived from myeloma proteins Ba (G3m(g+)) and Bu (G3m(g-)). The experimental results indicate that glutamic acid at position 295 is responsible for the specificity. Based on the results of chemical modification (Arg, Tyr, and Glu), this antigenic epitope is presumed to involve five sequential residues from Arg-292 to Tyr-296.
Journal
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- The Journal of Biochemistry
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The Journal of Biochemistry 99 (6), 1799-1802, 1986
The Japanese Biochemical Society
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Details 詳細情報について
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- CRID
- 1570572703010711040
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- NII Article ID
- 130006874715
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- Text Lang
- en
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- Data Source
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- CiNii Articles