能動輸送と受動輸送が共存する生体膜輸送の最適制御

3 References
  • HIRAYAMA H
    Department of Public Health Asahikawa Medical College
  • TSUBOI K
    Department of Public Health Asahikawa Medical College
  • TAKAHASHI O
    Department of Public Health Asahikawa Medical College
  • NISHIYAMA T
    Department of Public Health Asahikawa Medical College
  • FUKUYAMA Y
    Department of Public Health Asahikawa Medical College

Bibliographic Information

Other Title
  • Optimal Control of Membrane Transport Driven by Active and Passive Transport Mechanisms

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Description

生体膜を介しての物質輸送における最適制御で、能動輸送と受動輸送が共存する場合を理論的に解析した。系は細胞外空間、細胞膜内空間、細胞質の3つとした。細胞外から膜を経由して細胞質またその逆方向の輸送においてそれぞれ4つ、合計8個の輸送状態を考えた。受動輸送係数が変化しても細胞外空間、細胞質における粒子数変化の時間的経過は同一であった。細胞膜内空間での粒子数変化は受動輸送および能動係数により著しく影響された. 最適制御量としての能動輸送係数を変化させると能動輸送のために消費される最適制御量は著しく影響された。とくに細胞質から細胞膜内空間への最適能動輸送の時間経過は最大値を有する放物線状となった。本研究は能動輸送と受動輸送が共存するより生物学的膜輸送における制御およびそれらの相対的重要度を解析するのに有用である。
A theoretical approach has been utilized to analyze the membrane transport system that involves both active and passive transport mechanism. The system was simplified to 3 spaces, external world of cell, intra membrane and inside of cell. The basic time courses of amount of particle in the external world and intra membrane were insensitive to changes in passive transport rate. The change within membrane, however, was influenced considerably both by passive and active transport. The amount of the optimal control for active transport was influenced seriously by changes in the active transport rate as the optimal control. This effect was manifested particularly in the transport from inside of cell to the intra membrane space. Present theory is available for evaluation of the the relative importance between passive and active transport in biological membrane.

Journal

  • Technical report of IEICE. OME

    Technical report of IEICE. OME 96 (278), 1-6, 1996-09-27

    The Institute of Electronics, Information and Communication Engineers

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Details 詳細情報について

  • CRID
    1570854177467245824
  • NII Article ID
    110003300677
  • NII Book ID
    AN10013334
  • Text Lang
    en
  • Data Source
    • CiNii Articles

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