Muscle .BETA.-actinin is not chicken serum albumin.
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- MARUYAMA Koscak
- Department of Biology, Faculty of Science, Chiba University
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- KIMURA Sumiko
- Department of Biology, Faculty of Science, Chiba University
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説明
Recently, Heizmann et al. (Proc. Natl. Acad. Sci. U. S. 78, 74-77 (1981)) reported that muscle β-actinin and serum albumin of the chicken are indistinguishable by physicochemical and immunological criteria. It should, however, be stated that the protein the above authors called β-actinin was entirely different from genuine muscle β-actinin (Maruyama et al. (1977) J. Biochem. 81, 215-232). In the present study, it was experimentally shown that chicken serum albumin does not have any of the actions of β-actinin: inhibition of reassociation of F-actin fragments, retar-dation of depolymerization of F-actin, instability of F-actin, acceleration of polymerization of G-actin, and formation of Mg polymer. The role of muscle β-actinin, a heterodimer of 37, 000 and 34, 000 daltons, in the regulation of myofibrillar structure is summarized.
収録刊行物
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- The Journal of Biochemistry
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The Journal of Biochemistry 90 (2), 563-566, 1981
The Japanese Biochemical Society
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詳細情報 詳細情報について
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- CRID
- 1570854178110042880
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- NII論文ID
- 130003541879
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- ISSN
- 0021924X
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles