リンパ球性脈絡髄膜炎 (LCM) ウイルス抗体の検出

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書誌事項

タイトル別名
  • Detection of Lymphocytic Choriomeningitis Virus Antibody in Colonies of Laboratory Animals in Japan

抄録

Indirect fluorescent antibody method was applied for a detection of lymphocytic choriomeningitis virus (LCMV) antibody in colonies of laboratory animals in Japan. The results showed that the antibody exist in SPF mice (3/152, 2.2%) and conventional mice (30/539, 5.6%) with the titers ranging from 1: 10 to 1: 160. The antibody was also detected in 2.2% (2/89) of Syrian hamsters, and 2.9% (2/68) of Apodemus agrarius, 21.4% (3/14) of Japanese harvest mice which have been maintained as laboratory colony for several years. However, the antibody was not demonstrated in Mongolian gerbils, Suncus murinus, guinea pigs and rats, thus far. These results indicate that LCMV infection is present in laboratory animals in Japan, and pointed out the importance of microbiological monitoring for LCMV.

収録刊行物

  • Experimental Animals

    Experimental Animals 35 (2), 189-192, 1986

    公益社団法人 日本実験動物学会

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