Bioactive Saponins and Glycosides. IV. 1) Four Methyl-Migrated 16, 17-seco-Dammarane Triterpene Glycosides from Chinese Natural Medicine, Hoveniae Semen Seu Fructus, the Seeds and Fruit of Hovenia dulcis THUNB.: Absolute Stereostructures and Inhibitory Activity on Histamine Release of Hovenidulciosides A_1, A_2, B_1, and В_2

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Abstract

Four bioactive methyl-migrated 16,17-seco-dammarane type triterpene glycosides called hovenidulciosides A_1,A_2,B_1,and B_2 were isolated from a Chinese natural medicine, Hoveniae Semen seu Fructus, the seeds and fruit of Hovenia dulcis THUNB. (Rhamnaceae) together with hoduloside III and (+)-gallocatechin. The absolute stereostructures of hovenidulciosides A_1,A_2,B_1,and B_2 have been elucidated by chemical and physicochemical evidence. All were found to inhibit the histamine release from rat peritoneal exudate cells induced by compound 48/80 and calcium ionophore A-23187.

Journal

  • Chem. Pharm. Bull.

    Chem. Pharm. Bull. 44 (9), 1736-1743, 1996-09-15

    The Pharmaceutical Society of Japan

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Details 詳細情報について

  • CRID
    1571698602302057344
  • NII Article ID
    110003632154
  • NII Book ID
    AA00602100
  • ISSN
    00092363
  • Text Lang
    en
  • Data Source
    • CiNii Articles

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