Liquid phase immunoassay utilizing magnetic marker and high Tc superconducting quantum interference device
書誌事項
- 公開日
- 2006-09-01
- 公開者
- American Institute of Physics
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説明
We have developed a liquid phase immunoassay system utilizing a magnetic marker and a superconducting quantum interference device (SQUID). In this system, the magnetic marker was used to detect the biological material called antigen. The magnetic marker was designed so as to generate a remanence, and the remanence field of the markers that bound to the antigens was measured with the SQUID. The measurement was performed in a solution that contained both the bound and free (or unbound) markers, i.e., without using the so-called bound/free (BF) separation process. The Brownian rotation of the free markers in the solution was used to distinguish the bound markers from the free ones. Using the system, we conducted the detection of biological material called IgE without BF separation. At present, we could detect the IgE down to 7 pg (or 39 amol)
収録刊行物
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- Journal of Applied Physics
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Journal of Applied Physics 100 (5), 54701-1-054701-5, 2006-09-01
American Institute of Physics
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詳細情報 詳細情報について
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- CRID
- 1571698602559282944
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- NII論文ID
- 120002440559
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- NII書誌ID
- AA00693547
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- ISSN
- 00218979
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- Web Site
- http://hdl.handle.net/10228/341
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- 本文言語コード
- en
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- データソース種別
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