Relation between Myocardial Contractility and Stiffness in Clinical Cases

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Description

Left ventricular myocardial stiffness was evaluated in 50 patients who underwent cardiac catheterization. Left ventricular cineangiograms and simultaneously recorded left ventriculr pressure tracings were analyzed. The left ventricular stiffness constant k was computed by substituting the left ventricular myocardial stress (σ) and strain (ε) throughout the period between the end of rapid filling and the beginning of atrial contraction in the equation σ=b・e^<κ・ε>. Left ventricular myocardial stiffness constants were measured as follows: Group I (normal, 9)-10.0±3.8, Group II (mitral stenosis, 8)-10.4±3.4, Group III (left ventricular volume overload, 11)-11.7±3.4, Group IV (coronary artery disease without myocardial infarction, 10)-8.9±2.2, and Group V (myocardial infarction, 12)-20.1±7.9. All of the normal cases showed stiffness constants of less than 15 and maxVcf of more than 2.0 circ./sec., and all of the patients with heart failure in Groups III-V showed stiffness constants of more than 15 and maxVcf of less than 1.0 circ./sec. Thirteen patients who had surgical indications and who also did not have increased myocardial stiffness (k less than 15) with or without abnormal values of contractility indices underwent corrective cardiac surgery with satisfactory results and normal morphological findings in myocardium. Thus, assessment of left ventricular myocardial stiffness offers useful additional information concerning cardiac status in clinical cases.

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Details 詳細情報について

  • CRID
    1571980076879232384
  • NII Article ID
    110004690463
  • NII Book ID
    AA00863975
  • ISSN
    03850005
  • Text Lang
    en
  • Data Source
    • CiNii Articles

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