Drug-Induced False Positive Tests for Protein in Urine Specimens from the Automated Multiphasic Health Testing Services of Tokai University Hospital

TADANO Jutaro, NIWA Masaharu, HINOHARA Shigeo, SHIOYA Sumie, SUZUKI Sotaro

Drug-Induced False Positive Tests for Protein in Urine Specimens from the Automated Multiphasic Health Testing Services of Tokai University Hospital

TADANO Jutaro

Department of Clinical Pathology, School of Medicine Tokai University
NIWA Masaharu

Department of Clinical Pathology, School of Medicine Tokai University
HINOHARA Shigeo

Center of Automated Multiphasic Health Testing Services, Tokai University Hospital
SHIOYA Sumie

Center of Automated Multiphasic Health Testing Services, Tokai University Hospital
SUZUKI Sotaro

Center of Automated Multiphasic Health Testing Services, Tokai University Hospital

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説明

Since the Albustix strip was introduced in 1957, urine protein dipsticks have been used in routine urinalysis, and their convenience and clinical usefulness have been well established. There are many reports on false-positive results of urine protein dipsticks under various conditions. False-positive results can be obtained if the strip is kept immersed in the urine sufficiently long for the citrate buffer to be dissolved out. False-positive results are also sometimes obtained when the urine has a high buffer capacity and high pH. Some authors maintain that various kinds of drugs such as radiographic contrast media and ammonium salts give rise to false-positive results. There has as yet been no report concerning digestants. The purpose of the present paper is to describe digestant-induced interference in urine protein tests of specimens from the AMHTS of the Tokai University Hospital.