Extracellular Matrix Formed by MC3T3-E1 Osteoblast-Like Cells Cultured on Titanium : I. Anchor Structure :

  • YAMASHITA,Kikuji
    Department of Anatomy, School of Dentistry, University of Tokushima
  • EGUCHI,Satoru
    Department of Dental Anesthesiology, School of Dentistry, University of Tokushima
  • MORIMOTO,Hiroyuki
    Department of Anatomy, School of Dentistry, University of Tokushima
  • HANAWA,Takao
    Biomaterial Center, National Institute for Materials Science
  • ICHIKAWA,Tetsuo
    Department of Removable Prosthodontics, School of Dentistry, University of Tokushima
  • NAKAJO,Nobuyoshi
    Department of Dental Anesthesiology, School of Dentistry, University of Tokushima
  • KITAMURA,Seiichiro
    Department of Anatomy, School of Dentistry, University of Tokushima

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抄録

In order to clarify the structure of the extracellular matrix formed by osteoblasts in contact with titanium, we analyzed the structure formed by cultured clonal MC3T3-E1 osteoblasts on a calcified surface of commercial pure titanium, after exfoliating the cells from the surface of the titanium. Collagen fibers formed between neighboring cells and between cells and titanium, in the latter case with one tip of each collagen fiber bound to the cell and the other tip bound to the surface of the titanium embedded in the calcified layer. We called this structure an "anchor structure", because the collagen fibers embedded in the calcified layer anchor the cells to the titanium. This structure may be a reason for the useful biocompatibility between titanium and bone.

収録刊行物

  • Connective tissue

    Connective tissue 36 (1), 1-8, 2004-04-08

    日本結合組織学会

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