Mutarotation of D-Glucose in Body Fluids and Perfused Rat Liver(Biological,Chemical)

被引用文献2件
  • 奥田 潤
    Department of Clinical Biochemistry, Faculty off Pharmacy, Meijo University
  • 田口 忠緒
    Department of Clinical Biochemistry, Faculty off Pharmacy, Meijo University
  • 富村 愛子
    Clinical Laboratory, Holy Spirit Hospital.

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説明

Mutarotation of D-glucose a and β-anomers in some human body fluids, physiological salt solutions, and perfused rat liver was measured by the β-D-glucose oxidase-mutarotase method or by polarimetry. The mutarotational half-lives of α-D-glucose at 20℃(37℃) were as follows: whole blood, 9.0min (2.3min); serum, 10.6min (2.5min); saliva, 22.4min (4.5min); urine, 17.9min (4.3min); and distilled water, 41.0min (9.8min). It seems that the rapid mutarotation of D-glucose in blood may be due to the presence of mutarotase, phosphate ions, and bicarbonate ions. The mutarotation of α-D-glucose infused into isolated rat liver, warmed at 37℃, was rapid (t_<1/2> = 7.2min), probably due to the presence of mutarotase in the liver, compared with that in the control system without liver (t_<1/2> = 50.3min). The anomeric composition of D-glucose released from the perfused rat liver was almost at equilibrium.

収録刊行物

  • Chem. Pharm. Bull.

    Chem. Pharm. Bull. 35 4332-4337, 1987

    公益社団法人日本薬学会

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詳細情報 詳細情報について

  • CRID
    1572824502162449152
  • NII論文ID
    110006281616
  • NII書誌ID
    AA00602100
  • ISSN
    00092363
  • 本文言語コード
    en
  • データソース種別
    • CiNii Articles

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