Evaluation of Various Benign Diseases with High Level of Serum CA19-9

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  • 良性疾患における血清CA19-9高値例の検討

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Various benign diseases with a serum CA19-9 level of over 100U/ml were evaluated. 1) The number of biliary tract disease, renal cyst and chronic pancreatitis were 10, 3 and 2 cases, respctively. Chronic hepatitis, rheumatoid arthritis and chronic thyroiditis with myoma uteri were 1 case each. 2) The level of serum CA 19-9 in cholelithiasis decreased with improvement of symptoms and after cholecystectomy. Renal cyst with urinary tract infection, chronic pancreatitis and chronic hepatitis also showed a decrease of serum CA19-9 with improvement of symptoms. However, the level of serum CA 19-9 increased gradually without relation to symptoms in one case of renal cysts and was constantly over 1,000U/ml in chronic thyroiditis with myoma uteri. 3) CA19-9 in B bile showed a strikingly high level of over 1,000U/ml in biliary tract disease and gastric ulcer without abnormality of biliary tract. From this data, it was suggested that the epithelium of the bile duct and gallbladder produced and secreted a large quantity of CA 19-9. In the future, the localization of CA 19-9 in tissues affected by various diseases and the mechanism of dispersion into the blood should be studied.

Journal

  • Kitasato medicine

    Kitasato medicine 15 (4), 259-264, 1985-08-31

    Kitasato University

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