PHOTOCHEMICAL SYNTHESIS OF ANTITUMOR PLATINUM PYRIMIDINE GREENS ; POSSIBLE CONTRIBUTION OF SINGLET OXYGEN(Communications to the Editor)
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- Okuno Yohmei
- National Chemical Laboratory for Industry(NCLI)
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- Inoue Takayuki
- Faculty of Pharmaceutical Sciences, Hokkaido University
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- Yonemitsu Osamu
- Faculty of Pharmaceutical Sciences, Hokkaido University
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- Tomohiro Takenori
- National Chemical Laboratory for Industry(NCLI)
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- Laitalainen Tarja
- National Chemical Laboratory for Industry(NCLI)
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Abstract
A method is given for the selective synthesis of antitumor platinum greens in a reaction of the hydrolysis products of cis- diiododiammineplatinum (II) and nucleosides via visible-light induced oxidation. A role of singlet oxygen in the green formation is indicated by the sensitized reactions with methylene blue and rose bengal and by experimental quenching of singlet oxygen with 1,4-diaza-bicyclooctane(DABCO).
Journal
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- Chemical & pharmaceutical bulletin
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Chemical & pharmaceutical bulletin 35 (7), 3074-3077, 1987-07-25
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1573387452115847296
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- NII Article ID
- 110006281369
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- NII Book ID
- AA00602100
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- ISSN
- 00092363
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- Text Lang
- en
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- Data Source
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- CiNii Articles
