COLLISION OF MULTICENTRIC CANCEROUS FOCI AGAINST EACH OTHER IN EXPERIMENTAL RAT LIVER CANCER

J-STAGE

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  • 実驗的多中心性ネズミ肝癌における初期癌巣間の相互交渉について

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1. Some examples of colliding tumors in experimental DAB rat liver cancers are presented.<br>2. All the tumors encountered in the experiment were examined histologically and classified. Their ranges of structural variation were determinated.<br>3. Histology of collision between two cancers, or of invasion of a tumor by a second and more potent tumor was described. Passive behavior of the invaded tumor was analogous to normal tissue under infiltration by a cancer.<br>4. End result of collision would most likely lead to occupation of the field by one tumor, superior to the other in proliferative potency.<br>5. Development of a cancer in a field of cancerization is by way of elimination of minor cancers in statu nascendi by a potent cancer, and not in the mode of appositional growth.

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