Regulation of blood oxygenation during short-term hypercapnia in the carp,Cyprinus carpio.

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Abstract 1. 1. In the carp, Cyprinus carpio , the P 50 was found to be 11. l Torr at 25°C and pH 7.9. The Bohr effect of −0.57 was also found. 2. 2. Arterial CO 2 tension increased linearly with the CO 50 tension of inspired water (P Ico 2 ), causing a corresponding decrease in arterial pH (pHa). 3. 3. Despite the decrease in pHa, O 2 saturation of hemoglobin in arterial blood was maintained at the normocapnic level up to a P co 2 of 60 Torr. 4. 4. The specific ventilatory flow rate changed little at a P Ico 2 of 4–15 Torr and increased at a P Ico 2 of 15–120 Torr. 5. 5. Arterial O 2 tension (PaO 2 ) increased with P Ico 2 and remained stable (around 90 Torr) at a P Ico 2 of 40–120 Torr. 6. 6. It is suggested that the blood oxygenation is maintained mainly by an increase in PaO 2 during short-term hypercapnia and that there are important mechanisms to increase PaO 2 other than hyperventilation during hypercapnia.

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詳細情報 詳細情報について

  • CRID
    1573950401077501056
  • NII論文ID
    30010477234
  • DOI
    10.1016/0300-9629(91)90440-n
  • ISSN
    03009629
  • データソース種別
    • CiNii Articles
    • OpenAIRE

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