A Case Report of Henoch-Schoenlein Purpura Nephritis Associated with a Postbulbar Duodenal Ulcer

  • MIURA Masahiko
    Department of Internal Medicine, School of Medicine, Tokai University
  • TOMINO Yasuhiko
    Department of Internal Medicine, School of Medicine, Tokai University
  • FUJIMOTO Takao
    Department of Surgery, School of Medicine, Tokai University
  • SHIBATA Harumichi
    Department of Internal Medicine, School of Medicine, Tokai University
  • SENOUE Issei
    Department of Internal Medicine, School of Medicine, Tokai University
  • ENDOH Masayuki
    Department of Internal Medicine, School of Medicine, Tokai University
  • KANESHIGE Hideaki
    Department of Internal Medicine, School of Medicine, Tokai University
  • NOMOTO Yasuo
    Department of Internal Medicine, School of Medicine, Tokai University
  • SAKAI Hideto
    Department of Internal Medicine, School of Medicine, Tokai University
  • ARIMORI Shigeru
    Department of Internal Medicine, School of Medicine, Tokai University

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Description

We experienced an adult patient with Henoch-Schoenlein purpura (HSP) nephritis associated with a postbulbar duodenal ulcer. Chronic inflammatory changes of the arterioles (i.e. vasculitis) in the kidney and skin were prominently observed by immunofluorescence and light microscopic analysis. It is postulated that a postbulbar duodenal ulcer occurred in this patient and was mediated by vascular deposition of circulating immune complexes. It was suggested that HSP nephritis is a diffuse vascular form of IgA nephropathy.

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