薬物過敏症の発症機序に関する研究
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- 宇野 勝次
- 福山大学
書誌事項
- タイトル別名
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- Study on the Pathogenic Mechanism of Drug Hypersensitivity
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説明
Drug hypersensitivity includes an allergic and pseudoallergic reaction to drug. Therefore, the pathogenic mechanism of drug hypersensitivity must be studied from two viewpoints of immunological reaction and pharmacological reaction. And it is necessary for the mechanism of drug allergy to be investigated m three phases, that is, an antigen formation, an immune reaction and an inflammatory reaction. Particularly, cytokines take an important part in the development of drug allergy. Besides, the cross-reactivity of β-lactam antibiotics in allergic reaction constitutes a serious problem on the secondary choice of antibiotics for the patients with allergy to β-lactam antibiotics. Then, I review the participation of cytokines in drug allergy, the cross-reactivity of β-lactam antibiotics in allergic reaction and further the pseudoallergic reaction to drug.
収録刊行物
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- 福山大学薬学部研究年報
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福山大学薬学部研究年報 25 1-20, 2007
福山大学
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詳細情報 詳細情報について
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- CRID
- 1573950402298534912
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- NII論文ID
- 110007408829
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- NII書誌ID
- AN10064550
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- ISSN
- 0288724X
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- 本文言語コード
- ja
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- データソース種別
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- CiNii Articles