Changes of HDL and Its Subfractions Constituents between Hepatic Vein and Femoral Artery

J-STAGE
  • TAKATA Kouki
    First Department of Internal Medicine, Hiroshima University School of Medicine
  • YAMAMOTO Masahiro
    First Department of Internal Medicine, Hiroshima University School of Medicine
  • HIND Fumiaki
    First Department of Internal Medicine, Hiroshima University School of Medicine
  • MATSUURA Hideo
    First Department of Internal Medicine, Hiroshima University School of Medicine
  • KUROGANE Hiroyuki
    First Department of Internal Medicine, Hiroshima University School of Medicine
  • KAJIYAMA Goro
    First Department of Internal Medicine, Hiroshima University School of Medicine

Bibliographic Information

Other Title
  • 肝静脈および大腿動脈血流中における血中HDLおよびその亜分画成分の変化

Abstract

The difference in HDL-lipid constituents were examined between hepatic vein and femoral artery. in HDL, HDL2 and HDL3 most pronounced difference was found in triglyceride concentration which was significantly higher in femoral artery as compared to hepatic vein. Cholesterol and phospholipid concentration of HDL2 alone but not of HDL3 was also significantly higher in femoral artery than hepatic vein. Concentration of Apo A-I and A-II, on the other hand, remained unaltered in the blood circulation. These results in combination with the result that significant decrease of triglycerides of VLDL and LDL fraction (d=1.006-1.063) was observed in femoral artery as compared to hepatic artery, suggest that the accumulation of triglycerides in HDL is due to their transfer from other triglyceride-rich lipoprotein and accumulation of HDL 2b occurs in the blood stream from hepatic vein to femoral artery.

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