Visualization of Interval Changes of Pulmonary Nodules Using High-Resolution CT Images

2 Citations 26 References

Search this article

Abstract

This paper presents a method to analyze volumetrically evolutions of pulmonary nodules for discrimination between malignant and benign nodules. Our method consists of four steps; (1)The 3-D rigid registration of the two successive 3-D thoracic CT images, (2)the 3-D affine registration of the two successive region-of-interest(ROI)images, (3)non-rigid registration between local volumetric ROIs, and(4)analysis of the local displacement field between successive temporal images. In the preliminary study, the method was applied to the successive 3-D thoracic images of two pulmonary nodules including a metastasis malignant nodule and a inflammatory benign nodule to quantify evolutions of the pulmonary nodules and their surrounding structures. The time intervals between successive 3-D thoracic images for the benign and malignant cases were 150 and 30 days, respectively. From the display of the displacement fields and the contrasted image by the vector field operator based on the Jacobian, it was observed that the benign case reduced in the volume and the surrounding structure was involved into the nodule. It was also observed that the malignant case expanded in the volume. These experimental results indicate that our method is a promising tool to quantify how the lesions evolve their volume and surrounding structures.

Journal

  • IEICE Trans. Inf. & Syst., D

    IEICE Trans. Inf. & Syst., D 85 (1), 77-87, 2002-01-01

    The Institute of Electronics, Information and Communication Engineers

Citations (2)*help

See more

References(26)*help

See more

Keywords

Details 詳細情報について

  • CRID
    1574231877209062144
  • NII Article ID
    110003210600
  • NII Book ID
    AA10826272
  • ISSN
    09168532
  • Text Lang
    en
  • Data Source
    • CiNii Articles

Report a problem

Back to top