Pituitary and Plasma Levels of Growth Hormone (GH), Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in Hereditary Dwarf Rats (<I>rdw/rdw</I>)

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  • UMEZU Motoaki
    <I>Laboratory of Animal Reproduction, Faculty of Agriculture, Tohoku University</I>
  • KAWADA Kenji
    <I>Laboratory of Animal Reproduction, Faculty of Agriculture, Tohoku University</I>
  • MIWA Akemi
    <I>Laboratory of Animal Reproduction, Faculty of Agriculture, Tohoku University</I>
  • ISHII Shinichi
    <I>Laboratory of Animal Reproduction, Faculty of Agriculture, Tohoku University</I>
  • MASAKI Junji
    <I>Laboratory of Animal Reproduction, Faculty of Agriculture, Tohoku University</I>

Bibliographic Information

Other Title
  • 遺伝性侏儒症モデルラット (<I>rdw/rdw</I>) の下垂体および血中の成長ホルモン (GH) , 卵胞刺激ホルモン (FSH) と黄体形成ホルモン (LH) 水準

Abstract

Koto et al found a new hereditary dwarf mutation from breeding colony of Wistar-Imamichi rat and named‘rdw’. To characterize endocrinological functions inrdwrats, pituitary and plasma levels of pituitary hormones including growth hormone (GH), follicle stimulating hormone (FSH) and luteinizing hormone (LH) were compared betweenrdwand normal rats. The hormone levels were estimated with radioimmunoassay (RIA) . It was found that pititary and plasma levels of GB ofrdwwere drastically decreased and those of FSH and LB were inclined to decrease but not remarkable as compared with normal. Rats ofrdwwere, therefore, considered to be useful as a model animal for endocrinological defects.

Journal

  • Experimental Animals

    Experimental Animals 40 (4), 511-515, 1991

    Japanese Association for Laboratory Animal Science

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