Production of daunorubicin by immobilized growing Streptomyces peucetius cells
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説明
Streptomyces peucetius cells were immobilized by entrapment in calcium alginate and a photosensitive synthetic polymer, and used for the production of daunorubicin (daunomycin), which is known to be an antitumour reagent. The use of cultivation media removed insoluble components in a natural medium prevented rapid decrease in daunorubicin titer after maximum production. These entrapped cells could be used at least five times for repeated daunorubicin production; the total cultivation period was 45 days.
収録刊行物
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- Applied Microbiology and Biotechnology
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Applied Microbiology and Biotechnology 27 1987-11-01
Springer Science and Business Media LLC