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Neuropathogenicity of Mutant Strains of Mouse Hepatitis Virus, 1a and 2c, from DBT Cells Persistently Infected with JHM Strain
Description
Two plaque mutants 1a and 2c of the mouse hepatitis virus JHM strain (MHV-JHM) from persistently infected DBT cells2 were examined for neuropathogenicity in mice. The mutant strains had peplomer proteins different from those of the original MHV-JHM3 and they were plaque purified.