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    • Hyperunstable Hemoglobin Koriyama Anti-HB Gun Hill Insertion of Five Residues in the β Chain

    DOI PubMed

    書誌事項

    公開日
    1988-01-01
    DOI
    • 10.3109/03630268808998032
    公開者
    Informa UK Limited

    この論文をさがす

    説明

    A new hyperunstable hemoglobin was found in a Japanese girl who had very severe, chronic hemolytic anemia. Her parents and siblings were hematologically normal. The abnormal hemoglobin comprised a very small proportion of the total hemoglobin, although it was produced almost at the same rate as normal hemoglobin. Sequencing of an abnormal peptide which was liberated from the beta chain by hydrolysis with a protease from Staphylococcus aureus V8 disclosed the tandem insertion of a five-residue segment which included the proximal histidine at beta 92(F8).

    収録刊行物

    • Hemoglobin

      Hemoglobin 12 311-321, 1988-01-01

      Informa UK Limited

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