Dearomatization of 3-cyanoindoles by (3 + 2) cycloaddition: from batch to flow chemistry
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説明
<p>(3 + 2) Dearomatizing cycloaddition of 3-cyanoindoles occurs in smooth conditions with a non-stabilized azomethine ylide, to yield tricyclic indolines in only 1 min under microflow conditions using 3 equiv of the dipole precursor<italic>vs.</italic>6 equiv. in a batch reactor.</p>
収録刊行物
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- Organic & Biomolecular Chemistry
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Organic & Biomolecular Chemistry 18 3481-3486, 2020-01-01
Royal Society of Chemistry (RSC)