<title>Vacuum-cored hollow waveguide for high-energy high-intensity laser transmission and its application to biological tissue ablation</title>

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To suppress the laser-induced air breakdown which limited the transmission of 1064-nm Q-switched Nd:YAG laser pulses through hollow waveguide, a vacuum cell was attached to the waveguide ends, where the air was expelled for the cells as well as from the waveguide core region. With this scheme, the laser-induced air breakdown was completely suppressed, and in addition, the laser-induced damage threshold of the waveguide coating materials was significantly increased. Wit a 1-mm inner diameter, 1-m long, cyclic-olefin-polymer- coated silver hollow waveguide, a maximum transmitted laser energy reached approximately 200 mJ/pulse at 10 Hz in a straight waveguide condition. In a 90 degree-bent waveguide condition the laser-induced damage to the waveguide inner coating was observed, but a maximum transmitted energy in excess of 150 mJ/pulse at 10 Hz was obtained without any damage. With the transmitted laser pulses, sharp ablation in porcine myocardium tissues was demonstrated in vitro.© (2000) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

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