Studies on LDH isozyme in human contracted kidney and in rabbit kidney after renal arterial stenosis

DOI PubMed

Search this article

Description

Abstract The LDH isozymes in human contracted kidney of chronic renal failure and in rabbit kidney after renal arterial stenosis have been studied. In the human contracted kidney, the cortical and medullary tissues showed considerably less LDH I and LDH II activity, compared with normal kidney. Similar results were found in rabbit kidney after unilateral renal arterial stenosis. In normal human and animal kidney, the cortical and medullary tissues exhibited strong LDH I and LDH II activity. In the papillary tissues, on the contrary, the activity of LDH IV and LDH V was high. These findings and animal experimental results suggest that in the contracted kidney where O 2 consumption is decreased, carbohydrate metabolism is mainly anaerobic.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top