AB1198 The differences of the distribution of feeding vessels and bone surface irregularity between young and elderly adults in wrist joints of healthy volunteers by musculoskeletal ultrasound (MSKUS)

Background Synovial vascularity as measured by power Doppler (PD) of MSKUS is correlated to rheumatoid arthritis disease activity, and PD signal reveals the prevalence of subclinical synovitis overlooked on physical examination. It is often difficult to distinguish bone erosion from normal concave surface of the bone, and it is necessary for us to be familiar with these normal structures well in evaluating disease activity by using MSKUS. Here we examine the age-specific differences of normal feeding vessels and bone surface irregularity between in wrist joints. Objectives To elucidate the differences of distribution of feeding vessels and bone surface irregularity in wrist joints both young and older adults among healthy volunteers. Methods The dorsal side of wrist joints was scanned with 2D-probe in healthy volunteers (young Results: The distribution of feeding vessels in younger healthy volunteers (n=30:mean age 32.2±8.0 y.o.) vs elderly healthy volunteers (n=21:mean age 66.0±7.2 y.o.) were near-Trapezoid (Rt100.0% vs 100.0%, Lt100.0% vs 100.0%:p=1.00),E.digitorum TS(Rt86.7% vs 81.0%:p=0.59, Lt66.7% vs 76.2%:p=0.47),E.digiti minimi TS(Rt30.0% vs 52.4%:p=0.11, Lt30.0% vs 66.7%:p=0.0089), near-Capitate (Rt23.3% vs 42.9%:p=0.14, Lt30.0% vs 47.6%:p=0.21), near-TFCC(Rt16.7% vs 19.0%:p=0.83, Lt30.0% vs 38.1%:p=0.56), distal radial side of radiocarpal joint(Rt20.0% vs 42.9%:p=0.08, Lt23.3% vs 28.6%:p=0.68), distal end of Ulna(Rt10.0% vs 42.9%:p=0.006. Lt16.7% vs 28.6%:p=0.31). feeding vessels from vascular channels were depicted at Lu(Rt53.3% vs 52.4%:p=0.95, Lt46.7 vs 66.7%:p=0.16), Radius(Rt20.0% vs 33.3%:p=0.29, Lt16.7% vs 23.8%:p=0.54), Triquetrum (Rt10.0% vs 42.9%:p=0.0057, Lt16.7% vs 33.3%:p=0.17) and Capitate(Rt6.7% vs 33.3%:p=0.013, Lt10%vs33.3%:p=0.0395). The bone surface irregularity as a transverse diameter (Mean ±S.D.) at Lu of dominant hand in both groups were 1.26±0.33 vs 1.14±0.2 mm:p=0.21, respectively. Conclusions: The frequency of feeding vessel’s distributions in elderly adults were significantly higher at E.digiti minimi TS, distal end of Ulna and Triquetrum/Capitate vascular channels compared to those of younger adults. It is suggested that these differences are crucial to evaluate the age-specific synovitis with ultrasound. Disclosure of Interest: None declared