A translocation between 3q21 and 12q24 in a patient with minimally differentiated acute myeloid leukemia (AML-MO)

Eishi Ashihara, Tohru Inaba, Masao Nakagawa, Toshiya Sumikuma, Takehisa Kikuta, Hideo Goto, Naohisa Fujita, Noboru Yamagata, Chihiro Shimazaki, Hideyo Hirai, Yoshikazu Sudo

doi:10.1016/s0165-4608(96)00339-1

Description

Only a small number of reports have described the cytogenetic analysis of minimally differentiated acute myeloid leukemia (AML, M0). We performed a cytogenetic analysis on a patient with AML (M0) with a normal platelet count. It revealed a chromosomal translocation between chromosome bands 3q21 and 12q24. 3q. Abnormalities in AML are known to be associated with normal or elevated platelet counts. 3q21 and 12q24 are common translocation sites in AML patients, but this is the first report of translocation t(3;12)(q21;q24) in an AML patient.

Journal

Cancer Genetics and Cytogenetics

Cancer Genetics and Cytogenetics 97 90-93, 1997-09-01

Elsevier BV

Details 詳細情報について

CRID: 1870865117543769728

DOI: 10.1016/s0165-4608(96)00339-1

ISSN: 01654608

Data Source

OpenAIRE

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