Anticardiolipin antibody in Henoch-Sch�nlein purpura and related vascular disorders

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To clarify the exact role of these phospholipid antibodies in vascular injury, ACL titers were examined in 24 patients with Henoch-Schonlein purpura (HSP) and other forms of cutaneous vasculitis. ACL titers for HSP were lower than for cutaneous polyarteritis nodosa (PNC) or Takayasu's arteritis, but were significantly higher than for normal controls, as is shown in Fig. 1. The patients with erythema nodosum or hypergammaglobulinemic purpura showed normal ACL titers. ACL titers for allergic vasculitis could not be determined in this study because of the difficulty to obtain the serum. Next, clinical analysis was performed on five HSP cases who showed elevated ACL titers (three elderly cases and two younger ones)

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