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Attachment of heavy metal to DNA molecules for rapid analysis
Description
Labeling of DNA has been studied using base-specific Rhodium (II) acetate [Rh/sub 2/(O/sub 2/CCH/sub 3/)/sub 4/] (Rh1) compound. First, DNA and Rh1 were mixed and the binding reaction was checked by electrophoresis of the complex. The result showed that some of DNA molecules were labeled by the Rh1. AFM observation also showed some overlapped DNA molecules. It suggests that DNA molecules could be cross-linked by Rh1 on the overlapped points.
Journal
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- Fourtieth IAS Annual Meeting. Conference Record of the 2005 Industry Applications Conference, 2005.
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Fourtieth IAS Annual Meeting. Conference Record of the 2005 Industry Applications Conference, 2005. 2 775-777, 2005-10-24
IEEE