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Basic Fibroblast Growth Factor Fused with Tandem Collagen-Binding Domains from
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Description
Basic fibroblast growth factor 2 (bFGF) accelerates bone formation during fracture healing. Because the efficacy of bFGF decreases rapidly following its diffusion from fracture sites, however, repeated dosing is required to ensure a sustained therapeutic effect. We previously developed a fusion protein comprising bFGF, a polycystic kidney disease domain (PKD; s2b), and collagen-binding domain (CBD; s3) sourced from the
Journal
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- BioMed research international
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BioMed research international 2018 2017-12-01
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