The studies on the functions of intestine (I) the fat absorption in the postoperative malabsorption states

We studied the intest inal absorpt ion of the pat ients with the postoperat ive malabsorpt ion by means of 131I-labeled triolein, a lbumin and oleic acid, and 6~ labeled v i tamin B12. The rate of absorpt ion was expressed by the excret ion rate in 72 hours feces af ter the oral administration of 2 pc /kg lSlIlabeled substances, and in 24 hours urine af ter the oral adminis t ra t ion of 0.5/~c 6~ vi tamin B12. lalI-labeled tr iolein seemed to be the most reliable substance for the absorpt ion test. The normal excret ion rate remained less than 2%. After the operat ion of gas t rointes t inal tract , all of the pat ients with weight loss resul ted in impaired absorpt ion of triolein and oleic acid. The excret ion rate of tr iolein reached over 10% in the half of these patients. 75% of the pat ients with l iver diseases resul ted in impaired absorpt ion of fat. In the pa t ien ts with the shor tening of small bowel (after resect ion or blind loop formation), the average excret ion rate of fa t was 23.1% (2.9~67.0). The postgastrectomic malabsorpt ion had 15.3% in fecal recovery. After the par t ia l resection of large bowel, the impairment in the absorption of t r iolein was very s l ight (average fecal recovery was 4.1%). Any liver damage provoked the malabsorpt ion of fat and prote in in these patients . Circulus vi t iosus between the l iver damage and malabsorpt ion s ta tes was clinically and exper imental ly confined.