Mechanical responses in potassium-depolarized smooth muscle of Mytilus edulis
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説明
Abstract 1. 1. The anterior byssal retractor muscle of Mytilus depolarized in isotonic KCl responded to externally applied Ca2+, St2+ and Ba2+ by a contracture. 2. 2. The Ca contracture in KCl was found even after the response to caffeine was completely eliminated. 3. 3. In isotonic KCl, a contracture in response to acetylcholine (ACh) was obtained only when the KCl solution contained more than 1.0 mM Ca2+. 4. 4. Co2+, Ni2+ and Mn2+ reduced both the Ca contracture and ACh contracture. 5. 5. The results suggest that these contractures are brought about by Ca2+ which enters through the cell membrane. 6. 6. Serotonin reduced contractures in response to all of these agents, an effect consistent with a hypothesis that it lowers intracellular Ca2+ levels.
収録刊行物
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- Comparative Biochemistry and Physiology Part A: Physiology
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Comparative Biochemistry and Physiology Part A: Physiology 47 61-70, 1974-01-01
Elsevier BV