Effects of two different doses of leuprolide acetate depot on uterine cavity area in patients with uterine leiomyomata
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説明
To compare the effects of two different doses of a monthly depot injection of a GnRH agonist (GnRH-a) on uterine cavity area in patients with uterine leiomyomata.Prospective, randomized study.Hospital department of obstetrics and gynecology.Thirty-six premenopausal women, 25 to 52 years of age, with uterine leiomyomata.Leuprolide acetate (LA) depot, 1.88 or 3.75 mg, was administered SC every 4 weeks for 24 weeks.Uterine cavity area before and after treatment was assessed by hysterosalpingography.The 1.88- and 3.75-mg LA depots significantly reduced uterine cavity area by 40.8% and 40.2%, respectively. No significant difference was observed between the two groups.Monthly injection of 1.88 or 3.75 mg LA depots appears to reduce uterine cavity area to a similar extent in patients with uterine leiomyomata.
収録刊行物
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- Fertility and Sterility
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Fertility and Sterility 63 487-490, 1995-03-01
Elsevier BV