Synthesis of Some Analogues Of 1-[(2-Hydroxyethoxy)-methyl]-6-(phenylthio) Thymine (HEPT) which have Different types of Acyclic Structures

説明

Analogues of a recently developed specific anti-HIV-1 agent HEPT, 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine, having different types of acyclic moieties were synthesized based on lithiation chemistry. Anti-HIV-1 activity of these analogues is also described.

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