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Summary 1) Twenty autopsy cases of cerebral and pons glioma in this Clinic in these three years were taken to investigate the relationship between remaining nerve fibers in tumor and clinical manifestations. 2) The degree of decrease in nerve fibers in the tumor has been classified into I, II, III and IV degree in accordance with the number of preexisting nerve fibers still maintaining their normal histologic features. 3) The less malignant a glioma is clinically and histologically, the more nerve fibers are found still preserved. 4) In case of I or II degree of diminution the remaining nerve fibers often maintain their original functions. This tendency is more remarkable in pons gliomas. 5) Unduly slight clinical manifestations considering the localization of the tumor, as is often the case in patients with benign cerebral gliomas, may be due to the preservation of nerve fibers in the tumor. 6) Some gliomas grow expansively and not infiltratively. In such gliomas no nerve fibers are found even if they are histologically benign. This is to be considered as the result of nerve fibers being pushed aside and not being destroyed. In conclusion many thanks should be expressed to Prof. Masaya Araki. Professor of Pathology at the Kyoto Prefectural Medical School for his kind help in the staining techniques.
収録刊行物
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- Psychiatry and Clinical Neurosciences
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Psychiatry and Clinical Neurosciences 11 274-294, 1957-12-01
Wiley