The Productivity of Drug Development: A Systematic Review

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The evaluation of the productivity of research and development (RD however, there is no consensus on a unified criteria. To resolve this issue, we present a comprehensive review of previous studies on the topic. Publication databases were searched for all relevant studies related to the following: the pharmaceutical industry, RD a total of 6,357 publications were obtained. Through in-depth screening, 190 publications were selected and subsequently reviewed. As a result, methods for the evaluation of pharmaceutical RD increase in RD effectiveness of outsourcing; size of the company; and premiums and amortization with mergers and acquisition (M&A). By forming an intellectual basis for the evaluation procedures, the present study has contributed to the theory of R&D management and to the practices used in the pharmaceutical industry.

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