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説明
Immunohistochemical staining with anti-androgen receptor (AR) antibody was performed in skeletal muscle specimens obtained from 3 cases with bulbo-spinal muscular atrophy (BSMA) and 12 cases with other neuromuscular disease. Anti-AR antibody staining was found exclusively in the muscle nuclei of Type 2A fibers in all of the 3 cases. But there was no positive staining in the muscle nuclei of other disease. As above mentioned, very specific immuno-staining of AR in skeletal muscle would be of benefit to diagnosis of BSMA in addition to identification of a mutation of AR gene.
収録刊行物
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- Muscle & Nerve
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Muscle & Nerve 18 549-551, 1995-05-01
Wiley
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キーワード
詳細情報 詳細情報について
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- CRID
- 1871428068214781696
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- ISSN
- 10974598
- 0148639X
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- データソース種別
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- OpenAIRE
