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説明
7β-Hydroxycholesterol-14C was administered to bile-fistula rats, whose bile was collected and analyzed. As the major metabolites of this hydroxy sterol, the following unsaturated C24-bile acids were identified: the 4 possible stereoisomers of 3,7-dihydroxychol-5-enoic acid as well as those two of 3-hydroxy-7-oxochol-5-enoic acid. In addition, cheno- and ursodeoxycholic acids were indentified as minor metabolites. The meaning of these findings was discussed.
収録刊行物
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- Steroids
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Steroids 15 303-326, 1970-03-01
Elsevier BV