Are wall thickness channels defined by computed tomography predictive of isthmuses of postinfarction ventricular tachycardia?
説明
Wall thickness (WT) in post-myocardial infarction scar is heterogenous, with channels of relatively preserved thickness bordered by thinner scar.This study sought to determine whether 3-dimensionally-reconstructed computed tomography (CT) channels correlate with electrophysiological isthmuses during ventricular tachycardia (VT).We retrospectively studied 9 postinfarction patients (aged 57 ± 15 years, 1 female) with 10 complete VT activation maps (cycle length 429 ± 77ms) created using high-resolution mapping. Three-dimensionally-reconstructed WT maps from CT were merged with the activation map during sinus rhythm (SR) and VT. The relationship between WT and electrophysiological characteristics was analyzed.A total of 41 CT channels were identified (median 4 per patient), of median (range) length 21.2 mm (17.3-36.8 mm), width 9.0 mm (6.7-16.5 mm), and area 1.49 cmVT isthmuses were always found in CT channels (100% sensitivity), and half of CT channels hosted VT isthmuses (positive predictive value 51%). Longer and thinner (but1 mm) CT channels were significantly associated with VT isthmuses.
収録刊行物
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- Heart Rhythm
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Heart Rhythm 16 1661-1668, 2019-11-01
Elsevier BV
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キーワード
- Male
- Myocardial Infarction
- Contrast Media
- MUSIC
- Cicatrix
- Imaging, Three-Dimensional
- [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
- Heart Conduction System
- [INFO.INFO-IM]Computer Science [cs]/Medical Imaging
- Humans
- Contrart-enhanced multidetector computed tomography
- Retrospective Studies
- Wall thickness
- Ventricular tachycardia
- Middle Aged
- Isthmus
- Myocardial infarction
- Tachycardia, Ventricular
- High-resolution mapping
- Female
- Electrophysiologic Techniques, Cardiac
- Tomography, X-Ray Computed