Transforming Growth Factor‐β Regulates Susceptibility of Epithelial Apoptosis in Murine Model of Colitis
この論文をさがす
説明
<jats:p><jats:bold>A<jats:sc>bstract</jats:sc>: </jats:bold> Transforming growth factor (TGF)‐beta has a key role in intestinal homeostasis. Our present data suggest that TGF‐beta, which was constitutively expressed by lamina propria mononuclear cells and epithelium, affected epithelial cells. Abnormal suppression of TGF‐beta could enhance the sensitivity of epithelial cells to apoptosis associated with interferon‐gamma in DSS‐induced colitis.</jats:p>
収録刊行物
-
- Annals of the New York Academy of Sciences
-
Annals of the New York Academy of Sciences 1029 382-384, 2004-12-01
Wiley