Synthesis of marine bisindole alkaloids, hamacanthins A and B through intramolecular transamidation–cyclization

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Abstract The total syntheses of the marine bisindole alkaloids, hamacanthins were achieved by a novel transamidation–cyclization of N-(2-aminoethyl)-2-oxoethanamides to 3,5- and 3,6-disubstituted piperazinones.

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