The effect of hypertonic solutions on contracture tension and volume in Mytilus smooth muscle

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Abstract 1. 1. The effect of hypertonic solutions (1.6 times the normal osmolarity) on ACh-and K-con-tractures and the fibre volume in the anterior byssal retractor muscle of Mytilus edulis was studied. 2. 2. The contracture tension was reduced by 20–50% in the NaCl-hypertonic solution, and almost eliminated in the sucrose-and glycerol-hypertonic solutions. 3. 3. The muscle weight decreased by less than 3% in the NaCl-hypertonic solution, and by 8–20% in the sucrose-and glycerol-hypertonic solutions. 4. 4. It is suggested that the osmotic shrinkage of the fibres is the main cause of the reduction of contracture tension rather than the increased ionic strength in the myoplasm.

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